14 years teaching

Research Area

Bioinformatics, molecular modelling, docking, molecular dynamics and simulation, protein design, QSAR analysis, microarray data analysis and database development, computational protein engineering, In�silico analysis of NGS data

Research Guidance

02 (ongoing)

International Publications

1. Satpathy, R, Acharya, S; Behera, R (2024). Computational design, docking, and molecular dynamics simulation study of RNA helicase inhibitors of dengue virus. Journal of Vector Borne Diseases | DOI: 10.4103/JVBD.JVBD_188_23 (on-line) [Index: Scopus; Impact Factor: ]
2. Minz, S., Pati, A. K., Mohapatra, M., Pati, U. C., Sahu, P., Acharya, P. K., ... & Satpathy, R. (2024). Patterns in behavioural sleep variables and social jetlag in elderly people of Western Odisha. Chronobiology International, 1-12. [Index: Scopus; Impact Factor: ]
3. Satpathy, R., & Acharya, S. (2023). Exploring the Mangrove Based Phytochemicals as Potential Viral RNA Helicase Inhibitors by in silico Docking and Molecular Dynamics Simulation Methods. Mathematical Biology and Bioinformatics, 18(2), 405-417 [Index: Scopus; Impact Factor: ]
4. Satpathy, R. (2022). In silico Tools and Techniques for Screening and Development of Peptide-Based Spike Protein Inhibitors against Novel Coronavirus (Sars-CoV-2). Jordan Journal of Biological Sciences, 15(5).729-738. [Index: Scopus; Impact Factor: ]
5. Satpathy, R., & Acharya, S. (2022). Development of a database of RNA helicase inhibitors (VHIMDB) of pathogenic viruses and in silico screening for the potential drug molecules. The EuroBiotech Journal, 6(3), 116-125 [Index: Scopus; Impact Factor: ]
6. Satpathy, R. (2020). In Silico modeling and docking study of potential helicase (nonstructural proteins) inhibitors of novel coronavirus 2019 (severe acute respiratory syndrome coronavirus 2). Biomedical and Biotechnology Research Journal (BBRJ), 4(4), 330-336. DOI: 10.4103/bbrj.bbrj_149_20 [Index: Scopus; Impact Factor: ]
7. Satpathy, R. (2020). Application of Molecular Docking Methods on Endocrine Disrupting Chemicals: A Review. Journal of Applied Biotechnology Reports, 7(2), 74-80. [Index: Scopus; Impact Factor: ]
8. Satpathy, R. (2019). Quantitative structure�activity relationship methods for the prediction of the toxicity of pollutants. Environmental Chemistry Letters, 17(1), 123-128. [Index: Scopus; Impact Factor: ]
9. Chigurupati S, Vijayabalan S, Karunanidhi A, Selvarajan KK, Nanda SS & Satpathy R (2019). Antidiabetic, antioxidant and in silico studies of bacterial endosymbiont inhabiting Nephelium lappaceum L. Ovidius University Annals of Chemistry, 30(2), 95-100. [Index: Scopus; Impact Factor: ]
10. Satpathy, R., Konkimalla, V. B., & Ratha, J. (2017). Microbial dehalogenation: 3-chloropropanoic acid (3-CPA) degradation as a case study. Microbiology, 86(1), 32-41. [Index: Scopus; Impact Factor: ]
11. Satpathy, R., Konkimalla, V. B., & Ratha, J. (2015). Application of bioinformatics tools and databases in microbial dehalogenation research: A review. Applied biochemistry and microbiology, 51(1), 11-20. [Index: Scopus; Impact Factor: ]
12. Satpathy, R., Konkimalla, V. B., & Ratha, J. (2016). In silico phylogenetic analysis and molecular modelling study of 2-haloalkanoic acid dehalogenase enzymes from bacterial and fungal origin. Advances in bioinformatics, 2016., Article ID 8701201, 10 page [Index: Scopus; Impact Factor: ]
13. Satpathy, R., Konkimalla, V. B., & Ratha, J. (2015). Computer Aided Design of a Luciferase Like Haloalkane Dehalogenase Enzyme by Homology Based Rational Protein Design (HRPD) Method. Journal of Applied Biotechnology Reports, 2(4), 315-323. [Index: Scopus; Impact Factor: ]
14. Satpathy, R., Konkimalla, V. B., & Ratha, J. (2015). In-silico gene co-expression network analysis in Paracoccidioides brasiliensis with reference to haloacid dehalogenase superfamily hydrolase gene. Journal of pharmacy & bioallied sciences, 7(3), 212-219. [Index: Scopus; Impact Factor: ]
15. Satpathy, R., & Dash, N. (2022). In silico screening and characterization of novel natural peptides as spike protein inhibitors of novel coronavirus (severe acute respiratory syndrome coronavirus 2). J Prev Diagn Treat Strat. Medico, 1, 54�62. [Index: Other; Impact Factor: ]
16. Satpathy, R., Konkimalla, V. B., & Ratha, J. (2015). In silico based prediction and correlation of dehalogenase enzyme activity of some haloalkane compounds by quantitative structure biodegradation relationship (QSBR) analysis. Current Environmental Engineering, 2(2), 122-126. [Index: Other; Impact Factor: ]

National Publications

1. Satpathy, R. (2023). In-silico Prediction of Drug Target, Molecular Modeling, and Docking Study of Potential Inhibitors against Burkholderia pseudomallei. [Index: WoS; Impact Factor: ]
2. Satpathy, R (2024). De novo transcriptome analysis of Argemone mexicana plant (SRR287649) and annotation for secondary metabolite producing genes. Research Journal of Biotechnology, 19(3).86-92. [Index: Scopus; Impact Factor: ]
3. Satpathy, R (2022). Application of Bioinformatics resources for mining of simple sequence repeats (SSRs) marker in plant genomes: An Overview. Research Journal of Biotechnology 17 (8), 136-143. [Index: Scopus; Impact Factor: ]
4. Satpathy, R. (2021). Evaluation of anti-diabetic nature of some Boswellic acid derivatives by Molecular docking method. Current Trends in Biotechnology and Pharmacy,15 (2),177-181 [Index: Scopus; Impact Factor: ]
5. Satpathy, R., Behera, R., & Padhi, C. (2019). Dyeplantdb: A database of dye yielding plants. Agrica, 8(1), 37-40. [Index: Other; Impact Factor: ]

International Conferences

1. Presented an e-poster entitled �Study of some phytochemicals as potential peptide deformylase inhibitors of pathogenic bacteria by using molecular docking methods� in the International E-Conference on "Exploring the Frontiers of In silico Drug Discovery: Trends, Challenges, and Opportunities" held on 28.07.2023, organized by M.S. Ramaiah University of Applied Sciences, Karanataka. [Index: ]
2. Presented an e-poster entitled �In-silico based prediction of novel drug targets in Streptococcus pneumoniae� in the 4th International conference on Environment, Agriculture, Human and Animal Health (ICEAHAH-2023) held on 13th & 14th May 2023, Organized by V Voice Society [Index: ]
3. Presented a paper entitled� In -silico phylogenetic study of Cecropin Peptides� in the International Conference on �Recent Innovations of Biological Research�, held on 17.03.2022-18.03.2022 organized by PSGR Krishnaamal College for Women, Coimbatore, Tamilnadu, India. [Index: ]
4. Presented an e-poster entitled �In-silico identification of CAP11 and Mytilin B peptides as potential spike protein inhibitors of novel coronavirus (SARS-CoV-2)� in the International Virtual Conference on Biological Innovations & Computational Exploration for Pandemic Challenges (BICPAC -22) held on 25th & 25th February 2022, Organized by Bishop Harbour College, Chennai [Index: ]
5. Presented an e-poster entitled �In-silico study of Spike glycoprotein mutation and ACE2 binding affinity in case of Indian Sars Cov2 isolates� in the International conference on Environment, Agriculture, Human and Animal Health (ICEAHAH-2021) held on 5th & 6th June 2021, Organized by V Voice Society [Index: ]
6. Presented a paper entitled �In silico based modeling study and prediction of antifungal property of plant defensin DM-AMP1 protein� in the International conference on plant science in post genomic Era, on 17th -19th February 2011 organized by Sambalpur University. [Index: ]

National Conferences

1. Presented a poster entitled �Comparative structural analysis of wild type and triple mutant versions of HPPK-DHPS enzyme of Plasmodium falciparum� in the National Conference on Emerging Trends in Biotechnology and Bioinformatics (ETBB-2024)" held on 11th and 12th March 2024 at Sambalpur University, Odisha. [Index: ]
2. Presented a poster entitled �In silico analysis of gene expression data from sensitive and resistant strains of Plasmodium falciparum and the identification of potential upregulated hub genes� in the National Conference on Artificial Intelligence in Biological Sciences" held on 12th and 13th February 2024 at Department of Bioinformatics. BJB Autonomous College, Bhubaneswar [Index: ]
3. Presented a poster entitled �In-silico screening, docking, and molecular dynamics simulation study of some phytochemicals as potential RNA helicase inhibitors of SARS-CoV-2� (Under OURIIP category) in the Odisha Research Conclave -2023 (ORC 3) held on 14th -16th November 2023, Organized by Odisha Higher Education Council, Govt. of Odisha and Sambalpur University, Odisha [Index: ]
4. Presented a paper entitled �Prediction of fish toxicity of some halogenated compounds by using the Quantitative Structure-Activity Relationship (QSAR) method� in BIODRASILLENCE, Organized by Department of Biotechnology, Vel Tech High Tech Dr. Rangarajan Dr. Sakunthala Engineering College, Chennai India on 27th and 28th April 2023. [Index: ]
5. Presented an e-poster entitled �Comparative protein-protein interaction network analysis of mammalian hepcidin antimicrobial peptides by using computational tools� in the Recent Innovations in Health and Life Science Research (RIHLSR-2023) organized on February 24-25, 2023 by Kakatiya University, Warangal. [Index: ]
6. Presented a poster entitled �In-silico comparative analysis of thermostable Mercuric reductase from Geobacillus thermoleovorans CCB_US3_UF5 and its counterpart mesophilic enzyme� in the 23rd Odisha Bigyan �O� Paribesh Congress (OBPC) organized on November 26-27, 2022 by Sambalpur University, Sambalpur. [Index: ]
7. Presented a poster entitled �Development of a database of RNA helicase inhibitors of pathogenic viruses and screening for the potential drug molecules by in-silico methods� (Under OURIIP category) in the Odisha Research Conclave -2022 (ORC 2) held on 14th -16th November 2022, Organized by Odisha Higher Education Council, Govt. of Odisha and Ravenshaw University, Cuttack. [Index: ]
8. Presented a poster entitled �Prevalence of Sarcopenia in the elderly population in Sambalpur District of Odisha: A case study� (Under COE category) in the Odisha Research Conclave -2022 (ORC 2) held on 14th -16th November 2022, Organized by Odisha Higher Education Council, Govt. of Odisha and Ravenshaw University, Cuttack. [Index: ]
9. Presented a paper entitled �Understanding the mechanism of microbial dehalogenation process by quantitative structure-activity relationship (QSAR) analysis� in the two-day national conference on �Innovative Trends in Biotechnology", held on 05.08.2022-06.08.2022, Organized by Department of Biotechnology, Vel Tech High Tech Dr. Rangarajan Dr. Sakunthala Engineering College, Chennai India [Index: ]
10. Presented an e-poster entitled �Identification of novel drug targets in Mycobacterium tuberculosis H37Rv; A computational approach� in the two-day national conference �New Trends and Innovations in Bioengineering (NTIB 2022)", held on May 30-31, 2022, Organized by Department of Biotechnology, Faculty of Engineering, at Karpagam Academy of Higher Education [Index: ]
11. Presented an e-poster entitled �Screening of Boswellic acid molecules as anti- diabetic compound: An in-silico study� in the virtual National conference on Transforming Trends in Life Sciences and Health Care held on 17th & 18th November 2021, Organized by Dwarka Doss Govedhan Doss Vaishnab College, Chennai. [Index: ]
12. Presented a poster entitled �Identification of potential helicase inhibitors of novel coronavirus 2019 (Sars-Co-V2) by molecular modeling methods� in the Odisha Research Conclave -2021 held on 13th & 14th November 2021, Organized by Odisha Higher Education Council, Govt. of Odisha and Utkal University, Bhubaneswar. [Index: ]
13. Presented a paper entitled �Identification of novel dehalogenase enzyme producing bacteria for microbial degradation of 3-Chloropropionic Acid (3 CPA)� in the National conference on Recent advances in Biotechnology and Biofuel (NRCB) held on 12th & 13th September 2016, Organized by Bilaspur University. [Index: ]
14. Presented a paper entitled �Docking study of some phytochemicals and experimental drug molecules with NS5 methyl transferase enzyme of dengue virus� in the one-day regional seminar on Biotechnological and computational approach for sustainable development on February 11, 2016 Organized by MSB, Bhubaneswar. [Index: ]
15. Presented a Poster entitled �Chloride �ion Proline interaction in Haloalkane dehalogenase: A computational approach� in the National seminar on Science Technology for Human Development, on 5th -6th December 2014, organized by Siksha �O� Anusandhan University. [Index: ]
16. Presented a paper entitled �Molecular dynamics study of caspase-8 protein in cryopreserved condition� in the National conference on tissue engineering prospects & challenges, 21st -22nd January 2011, organized by NIT Rourkela. [Index: ]
17. Presented a paper entitled �In silico based investigation of anti-renal cancer compounds by molecular docking method� in the National seminar on Vedic studies & information technology, on 23rd -24th August 2011 organized by Devsanskriti Viswavidyalaya. [Index: ]
18. Presented a paper entitled �Computational basis of gene annotation study of Hepatitis C virus genotypes� in the National conference on Recent advances in Biotechnology (NCRB-2011), on 6th December 2011 organized by MITS Rayagada. Presented a paper entitled �In silico study of NP antigenic peptide cross immunity among Indian 2009 and 1980 H1N1 viral strains� in the National Conference on Cellular and Molecular immunology, on 25th -26th September 2010, organized by Andhra University. [Index: ]
19. Presented a paper entitled �In-silico modeling and docking studies of antiviral drugs for Swine flu.� in the National conference on computational Biology (NCCB), on 28th -29th December 2009, organized by Siksha O Anusandhan University. [Index: ]

Graduate Level:

Post Graduate Level:

Biochemistry (103), Bioinstrumentaion (104), Biostatistics (202), Bioinformatics and computational Biology (303), IPR,Biosafety and Bioethics (403)

Award, Honours and Achievements

1. Best poster Presentation award ( in the National Conference on Artificial Intelligence in Biological Sciences 2024)
2. Best Presentation award ( in the 4th International conference on Environment, Agriculture, Human and Animal Health (ICEAHAH-2023) )
3. Won Second presentation Prize ( in the two-day national conference �New Trends and Innovations in Bioengineering (NTIB 2022))
4. Best Poster Presentation award ( in the International Virtual Conference on Biological Innovations & Computational Exploration for Pandemic Challenges (BICPAC -22))
5. Best oral Presentation award ( in the International conference on Environment, Agriculture, Human and Animal Health (ICEAHAH-2021))
6. Best Teacher Award (International Journal for Modern Trends in Science and Technology (IJMTST) in 2022)
7. CSIR-UGC -NET in Life science (2006)
8. GRADUATE APTITUTE TEST IN ENGINEERING, GATE (XL) (2002,2003,2007)

Books / Chapters Published

1. Satpathy, R. (2024). Application of Molecular Modeling Techniques to Investigate Phytochemicals as Prospective Anti-Malarial Agents. Converging Pharmacy Science and Engineering in Computational Drug Discovery, edited by Rati Kailash Prasad Tripathi and Shrikant Tiwari, IGI Global, 2024, pp. 116-139. https://doi.org/10.4018/979-8-3693-2897-2.ch006
2. Satpathy, R. (2023). Quantitative Structure-Activity Relationship (QSAR) Study of Potential Phytochemicals for the Development of Drugs Against Neurological Diseases. In Multidisciplinary Applications of Natural Science for Drug Discovery and Integrative Medicine (pp.1-21) IGI Global. ISBN: 9781668494639 DOI: 10.4018/978-1-6684-9463-9.ch001
3. Satpathy, R., & Acharya, S. (2023). In-Silico Structural Protein Mutation Analysis of some Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-Cov-2) Genomes from the Indian Origin. In Biotechnology: Recent Scopes and Dimensions (pp.122-140) I I P Iterative International Publishers. ISBN: 978-93-5747-035-3
4. Satpathy, R., & Ratha, J. (2023). Detection Strategies of some Halogenated Metabolites Obtainedfrom Microbial Dehalogenase Enzyme Activity: An Overview. In Biotechnology: Recent Scopes and Dimensions (pp.168-174) I I P Iterative International Publishers. ISBN: 978-93-5747-035-3
5. Satpathy, R. (2023). Toxicity Prediction of Endocrine Disrupting Chemicals (EDCs) by using Bioinformatics Methods. In Biotechnology: Recent Scopes and Dimensions (pp.244-259) I I P Iterative International Publishers. ISBN: 978-93-5747-035-3
6. Satpathy, R. (2022). Application of Bioinformatics in the Plant Pathology Research. In Advances in Agricultural and Industrial Microbiology (pp. 191-205). Springer, Singapore. ISBN: 978-981-16-9682-4. DOI: 10.1007/978-981-16-9682-4_11.
7. Satpathy, R., & Acharya, S. (2022). Phytochemicals from Mangroves and Their Anti-Viral Applications. In Handbook of Research on Advanced Phytochemicals and Plant-Based Drug Discovery (pp. 350-365). IGI Global. ISBN: 9781668451298 DOI: 10.4018/978-1-6684-5129-8.ch018.
8. Satpathy, R. (2022). Application of Bioinformatics Techniques to Screen and Characterize the Plant-Based Anti-Cancer Compounds. In Handbook of Research on Natural Products and Their Bioactive Compounds as Cancer Therapeutics (pp. 466-484). IGI Global. ISBN13: 9781799892588 DOI: 10.4018/978-1-7998-9258-8.ch021
9. Satpathy, R.(2021). Algae-Based Industrial Wastewater Treatment Methods and Applications. In Urban Mining for Waste Management and Resource Recovery (pp 1-16). CRC Press. ISBN: 9781003201076 (e book) DOI: 10.1201/9781003201076-11
10. Satpathy, R., Raut PR (2021). COVID-19: An Updated Insight of the Pandemic. In Fighting the COVID-19 Pandemic (pp 1-17). Intech Open. ISBN: 978-1-83968-246-9 (e book) DOI: http://dx.doi.org/10.5772/intechopen.99097
11. Satpathy, R. (2021). Artificial Neural Network (ANN) Techniques in Solving the Protein Folding Problem. In Advanced AI Techniques and Applications in Bioinformatics (pp 189-197). CRC Press. ISBN: 9781003126164 (e book) DOI: 10.1201/9781003126164-9
12. Satpathy, R. (2021). Application of Dehalogenase Enzymes in Bioremediation of Halogenated Pollutants: A Short Review. In Handbook of Research on Microbial Remediation and Microbial Biotechnology for Sustainable Soil (pp. 373-385). IGI Global. ISBN13: 9781799870623 (e book) DOI: 10.4018/978-1-7998-7062-3.ch014
13. Satpathy, R. (2021). Application of Some Medicinal Plants and Their Constituents in the Treatment of Diabetes Mellitus. In Treating Endocrine and Metabolic Disorders with Herbal Medicines (pp. 32-46). IGI Global. ISBN13: 9781799848080 (e book) DOI: 10.4018/978-1-7998-4808-0.ch002.
14. Satpathy, R. (2020). Therapeutic Importance and Application of Boswellic Acid from the Plant Boswellia serrata. In Advanced Pharmacological Uses of Medicinal Plants and Natural Products (pp. 302-315). IGI Global. ISBN13: 9781799820949 (e book) DOI:?DOI: 10.4018/978-1-7998-2094-9.ch016
15. Satpathy, R. (2019). Computational Tools and Techniques to Predict Aquatic Toxicity of Some Halogenated Pollutants. In Handbook of Research on the Adverse Effects of Pesticide Pollution in Aquatic Ecosystems (pp. 318-337). IGI Global. ISBN13: 9781522561118 e book) DOI: 10.4018/978-1-5225-6111-8.
16. Satpathy, R. (2018). Microbial Bioreactor Systems for Dehalogenation of Organic Pollutants. In Handbook of Research on Microbial Tools for Environmental Waste Management (pp. 319-340). IGI Global. ISBN: 9781522535416 (e book), DOI: 10.4018/978-1-5225-3540-9.ch015.
17. Satpathy, R. (2018). Quantitative Structure-Activity Modelling of Toxic Compounds. In Nanotechnology, Food Security and Water Treatment (pp. 313-331). Springer, Cham. ISBN: 978-3-319-70165-3, DOI: https://doi.org/10.1007/978-3- 319-70166-0_10.
18. Satpathy, R. (2017). Bioinspired Algorithms in Solving Three-Dimensional Protein Structure Prediction Problems. In Bio-Inspired Computing for Information Retrieval Applications (pp. 316-337). IGI Global. ISBN: 9781522523765 (e book), DOI: 10.4018/978-1-5225-2375-8.ch012 (SCOPUS)
19. Satpathy, R., Konkimalla, V. S. B., & Ratha, J. (2016). Fungal Dehalogenation: An Overview. In Environmental Biotechnology (pp. 141-154). Apple Academic Press., eBook ISBN: 978-1-77188-363-4, DOI: 10.1201/9781315366289-7. (SCOPUS)
20. Satpathy, R. (2016). Quantitative structure activity relationship (QSAR) study of some haloalkane compound properties with their aquatic toxicity feature. In Advanced engineering: Current prospective (pp. 111-119). Research India Publication, ISBN: 978-93-84443-44-3.
21. Satpathy, R. (2016). Role of mycorrhizal fungi in herbicide degradation In Environmental Biotechnology: A new approach (pp. 179-187, Daya publication. ISBN: 978-93-5124-736-4.
22. Satpathy, R. (2015). Halogenation by Fungi and applications. In New Dimensions in Microbiology (pp. 338-347). Lenin Media Private Limited, Delhi, India. ISBN: 978-93-85160-84-4.
23. Satpathy, R. (2014). Bioinformatics resources for plant sciences In Biotechnology: An over view, (pp. 53-65), Daya publication. ISBN: 978-93-5124-333-5.
24. BOOK : Computational protein design strategies for Biosensor construction by Raghunath Satpathy, Lambert Academic Publication (Germany), 2018, ISBN: 978-613-6-61883-8.
25. BOOK: Editor of the book Title: Biotechnology: Recent Scopes and Dimensions, Volume 1 (2023) Iterative International Publishers, India, ISBN: 978-93-5747-035-3
26. Satpathy, R. (2024). Artificial Intelligence Techniques in the Classification and Screening of Compounds in Computer-Aided Drug Design (CADD) Process. In Book: n book: Artificial Intelligence and Machine Learning in Drug Design and Development. Scrivener Publishing (Wiley). ISBN:9781394234196 (e book), DOI: https://doi.org/10.1002/9781394234196.ch15
27. Satpathy, R. (2024). Computational Approaches to Discover Novel Phytochemical Inhibitors Against Novel Coronavirus (Sars-CoV-2). In Book: Computational Biology in Drug Discovery and Repurposing. Apple Academic Press. ISBN: 9781003455424 (e book), DOI: https://doi.org/10.1201/9781003455424

Sponsored Projects

1. Investigation of antimalarial property of the Argemone Mexicana phytochemicals by targeting essential proteins of Plasmodium falciparum (GMU SEED FUND )
2. In-silico investigation of some novel RNA helicase inhibitors and their activity against pathogenic virus (OSHEC, Govt.of Odisha)

Seminar / Symposia / Workshops / Short term Course organized

1. Advances in Biotechnology for sustainable development
2. merging trends in Health and Disease

Members of Professional Bodies

1. Society for agricultural research and management (SARM) (Membership No. :SARMLMA231008)
2. Scholars Academic and Scientific Society SAS eminent fellow membership (SEFM) (Membership No.: SAS/SEFM/039/2021)
3. Indian Academicians and Researchers Association (IARA) (Membership No.: M/M � 1320)
4. Odisha Bigyan Academy (OBA) (Membership No.: 626)
5. Society for applied Biotechnology (SABT) (Membership No.: LM/147)

Extra Responsibility

1. IQAC Coordinator, School of Biotechnology, Gangadhar Meher University, Sambalpur
2. Board of Studies, M.Sc. Biotechnology Gangadhar Meher University, Sambalpur
3. Anti-Ragging committee Gangadhar Meher University, Sambalpur
4. Co-Principal Investigator, Centre of Excellence (CoE) Odisha Centre for Geriatrics and Gerontology (OCGG), Gangadhar Meher University, Sambalpur
5. Coordinator of the School of Botany
6. Course co-coordinator of 6-month certificate course on geriatric care